Titanium dioxide as used in sunscreens is commonly modified with other ingredients to ensure efficacy and stability. Examples of what are known as surface modifier ingredients used for titanium dioxide include stearic acid, isostearic acid, polyhydroxystearic acid, and dimethicone/methicone copolymer.
Titanium IV Oxide, commonly known as Rutile Titanium Dioxide (TiO2), is a highly valued compound with an array of applications across various industries due to its exceptional properties. It is a naturally occurring oxide of titanium, predominantly found in the mineral rutile, which is renowned for its high refractive index, excellent opacity, and strong UV resistance. This makes TiO2 a vital ingredient in products ranging from paints and coatings to cosmetics and sunscreen lotions.
Different dermal cell types have been reported to differ in their sensitivity to nano-sized TiO2 . Kiss et al. exposed human keratinocytes (HaCaT), human dermal fibroblast cells, sebaceous gland cells (SZ95) and primary human melanocytes to 9 nm-sized TiO2 particles at concentrations from 0.15 to 15 μg/cm2 for up to 4 days. The particles were detected in the cytoplasm and perinuclear region in fibroblasts and melanocytes, but not in kerati-nocytes or sebaceous cells. The uptake was associated with an increase in the intracellular Ca2+ concentration. A dose- and time-dependent decrease in cell proliferation was evident in all cell types, whereas in fibroblasts an increase in cell death via apoptosis has also been observed. Anatase TiO2 in 20–100 nm-sized form has been shown to be cytotoxic in mouse L929 fibroblasts. The decrease in cell viability was associated with an increase in the production of ROS and the depletion of glutathione. The particles were internalized and detected within lysosomes. In human keratinocytes exposed for 24 h to non-illuminated, 7 nm-sized anatase TiO2, a cluster analysis of the gene expression revealed that genes involved in the “inflammatory response” and “cell adhesion”, but not those involved in “oxidative stress” and “apoptosis”, were up-regulated. The results suggest that non-illuminated TiO2 particles have no significant impact on ROS-associated oxidative damage, but affect the cell-matrix adhesion in keratinocytes in extracellular matrix remodelling. In human keratinocytes, Kocbek et al. investigated the adverse effects of 25 nm-sized anatase TiO2 (5 and 10 μg/ml) after 3 months of exposure and found no changes in the cell growth and morphology, mitochondrial function and cell cycle distribution. The only change was a larger number of nanotubular intracellular connections in TiO2-exposed cells compared to non-exposed cells. Although the authors proposed that this change may indicate a cellular transformation, the significance of this finding is not clear. On the other hand, Dunford et al. studied the genotoxicity of UV-irradiated TiO2 extracted from sunscreen lotions, and reported severe damage to plasmid and nuclear DNA in human fibroblasts. Manitol (antioxidant) prevented DNA damage, implying that the genotoxicity was mediated by ROS.
The alarming fact of this study is that it was only conducted for 100 days, I have been wearing makeup daily for at least the last fifteen years & would have eaten kilo's of lipstick in my life time - what effects has this had on my system & health??
Reacting to the report, France’s ministers of health, agriculture and economy instructed the country’s food health and safety agency, Anses, to investigate whether the additive poses a risk for human health.
The study was said to be prompted by “growing concerns that daily oral… Intake is associated with an increased risk of chronic intestinal inflammation and carcinogenesis”, or cancer formation”.
Packaging containing this additive has been shown to decrease ethylene production in fruit, thus delaying the ripening process and prolonging shelf life (4Trusted Source).
FDA guidelines:Americans are eating too much salt. So the FDA wants food manufacturers to cut back on sodium.
When sourcing suppliers for B301 and B311 lithopone, it is essential to consider not only the price lists but also the quality assurance, consistency in supply, and the capability to meet volume requirements. Reputable suppliers often provide detailed technical data sheets and may offer samples for testing to ensure their products meet the specific needs of your operation.Stability and darkening:
There are several factors that can influence the cost of titanium dioxide from suppliers. One of the main factors is the availability of raw materials, specifically titanium ore. The cost of extracting and processing titanium ore can fluctuate, which can in turn affect the cost of titanium dioxide. Suppliers must also take into consideration the cost of energy and other resources needed for the production of titanium dioxide, such as labor and equipment. In conclusion, titanium dioxide stands as a testament to the power of chemistry in shaping modern industry. Its versatility and unique characteristics have made it an indispensable component across a wide range of applications. As scientists continue to uncover new uses and address environmental concerns, the future of titanium dioxide remains bright and full of potential.While the FDA maintains that the regulated use of titanium dioxide is safe, the European Food Safety Authority and some other experts warn of potential, serious health risks.
This white pigment composed of barium sulfate and zinc sulfide, is influenced by several market drivers and trends. One significant driver is the expanding demand for lithopone in the paint and coating industry, owing to its excellent hiding power and (ultraviolet) UV resistance. The construction sector also propels the market growth of this compound, as it is widely used in architectural coatings for its durability and weather resistance. Additionally, the rising popularity of lithopone in the plastic and rubber industries, driven by its ability to enhance product opacity and stability, contributes to market expansion. Trends in this compound market include a growing emphasis on eco-friendly alternatives, stimulating research and development of sustainable production processes. Furthermore, the increasing focus on product quality and performance, along with advancements in nanotechnology applications, presents new opportunities for lithopone market players. Overall, the evolving landscape of industries utilizing this compound underscores its dynamic market, driven by both traditional applications and emerging trends.
Calcium carbonate is a naturally occurring mineral that is found in rocks and minerals such as calcite, aragonite, and limestone. It is commonly used in industries such as paint, paper, plastics, and rubber as a filler and pigment. The manufacturing process of calcium carbonate involves extracting the mineral from quarries or mines, crushing and grinding it into a fine powder, and then purifying it through various chemical processes.
Research supports that applying titanium dioxide to the skin in the form of sunscreens, makeup, and other topical products does not pose any health risks.
Overall, the precipitation of titanium dioxide is a complex process that requires careful control of various factors to achieve the desired product properties. By optimizing the precipitation percentage and carefully monitoring the precipitation process, manufacturers can produce high-quality titanium dioxide that meets the stringent requirements of their customers in the paints, coatings, plastics, and cosmetics industries.
Below 20% substitution, it is recommended to replace 1 kg of TiO2 with 1 kg of lithopone supplier.
The manufacturing process of high-quality Rutile Titanium Dioxide in specialized factories is a complex and precise operation. These factories employ cutting-edge technology and rigorous quality control measures to ensure the optimal purity and performance of the final product. The process typically involves mining, chemical treatment, calcination, and finally, crystal formation. Each step is crucial in determining the whiteness, opacity, and durability of the TiO2. Anatase titanium dioxide is also known for its excellent color stability and retention properties. When exposed to light, heat, and other environmental factors, the pigment maintains its vibrant color and does not fade or degrade easily. This makes it an ideal choice for exterior paints and coatings that are exposed to harsh weather conditions.
If you're curious about whether something you’re eating contains titanium dioxide, you can check the ingredients list. But know that the FDA doesn’t require food makers to use its chemical name on an ingredients list. Instead, it could be listed as:
In conclusion, as a leading manufacturer of nano titanium dioxide, we are proud to offer high-quality products that meet the needs of our customers in a wide range of industries. With our focus on strength, UV resistance, and optical properties, our nano titanium dioxide products are sure to enhance the performance and appearance of a variety of applications. Customers can trust in our commitment to sustainability and environmental responsibility, knowing that they are getting a product that is not only top quality but also eco-friendly.