Hydroxypropyl methyl cellulose (HPMC) is a cellulose derivative that was first developed and used in industrial and food applications starting in the 20th century. Its exact origin in terms of discovery and initial development is difficult to attribute to a single individual or organization, as research and development of cellulose derivatives has involved many scientists and companies at different times.
HPMC is produced through a chemical process known as etherification, in which natural cellulose is treated with hydroxypropyl chloride and sodium methoxide. This process alters the chemical structure of cellulose, making it water-soluble and giving it desired properties as a thickener, stabilizer and film-forming agent.
Production and Use over Time:
The use of HPMC in industrial and food applications has grown significantly since the mid-20th century, when researchers began to more fully explore the potential uses of cellulose derivatives. Its ability to act as a thickener, emulsifier and stabilizer has increased its adoption in a variety of industries, including pharmaceuticals, cosmetics and food.
Topical preparations:
HEC is also an essential ingredient in the production of adhesives and sealants. Its thickening properties help to control the flow and application of the adhesive, ensuring a strong and uniform bond. In addition, HEC helps to improve the adhesion of the adhesive to a wide range of surfaces. Manufacturers Lastly, in the mining industry, HPMC is utilized as a drilling fluid additive to improve borehole stability and as a flocculant in mineral processing to aid in separation and recovery processes. Ensuring Safety with HPMC