The primary mechanism through which LOLA works is by enhancing the liver's ability to remove ammonia from the bloodstream. When the liver is compromised due to diseases such as cirrhosis, its capacity to process and excrete ammonia diminishes, leading to elevated levels of this toxic substance. By supplementing with LOLA, patients may experience improved ammonia clearance, thereby reducing the risk of hepatic encephalopathy—a condition characterized by confusion, altered levels of consciousness, and, in severe cases, coma.
On the other hand, excipients are the non-active components of a drug formulation that serve as vehicles for the API. They may enhance the stability of the medication, aid in the manufacturing process, improve taste, or assist in the drug's absorption in the body. Common excipients include fillers, binders, preservatives, and flavoring agents. For instance, lactose is often used as a filler in tablets, while magnesium stearate serves as a lubricant during production. Although they do not provide therapeutic effects, excipients can influence the bioavailability and efficacy of the active ingredients, making their selection critical in drug formulation.