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In a study published in the journal Environmental Toxicology and Pharmacology in 2020, researchers examined the effects of food additives titanium dioxide and silica on the intestinal tract by grouping and feeding mice three different food-grade particles — micro-TiO2, nano-TiO2, and nano-SiO2.  With all three groups, researchers observed changes in the gut microbiota, particularly mucus-associated bacteria. Furthermore, all three groups experienced inflammatory damage to the intestine, but the nano-TiO2 displayed the most pronounced changes. The researchers wrote: “Our results suggest that the toxic effects on the intestine were due to reduced intestinal mucus barrier function and an increase in metabolite lipopolysaccharides which activated the expression of inflammatory factors downstream. In mice exposed to nano-TiO2, the intestinal PKC/TLR4/NF-κB signaling pathway was activated. These findings will raise awareness of toxicities associated with the use of food-grade TiO2 and SiO2.”

  • our digestive tract through eating and drinking. 
  • our digestive tract through eating and drinking. 
  • What Is It?

    In the plastic industry, titanium dioxide serves as a crucial ingredient in creating vibrant colors and improving UV resistance. By incorporating TiO2 into their products, manufacturers can produce durable plastics that withstand exposure to sunlight without fading or degrading. This makes titanium dioxide an indispensable component in the production of outdoor furniture, automotive parts, and other items that require weather resistance.

    It’s produced through the sulfate or chloride process, which both involve treating titanium ore with sulfuric or hydrochloric acid to produce titanium sulfate or titanium chloride. These materials are then further processed to remove impurities and produce titanium dioxide in its final form.

    Anatase Titanium Dioxide, commonly known as food-grade titanium dioxide, is a versatile and widely used substance in the food industry. This compound is recognized for its exceptional properties, including its bright white color, high refractive index, and excellent stability. Due to these characteristics, it has become an essential ingredient in various food products, playing a crucial role in enhancing their appearance and shelf life.

    In addition to its pharmaceutical applications, barium sulphate is extensively utilized in the production of paints and coatings, where a bright white pigment is essential. The opacity and brightness provided by barium sulphate make it a popular choice in formulations for white and colored paints. Its non-toxic nature and excellent stability enhance its appeal in these products.


    Apart from its use in pigments and additives, titanium dioxide is also employed in the production of other chemicals Furthermore, titanium dioxide’s photocatalytic properties have led to its use in environmental applications

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    In January 2022, the average price of domestic titanium dioxide in local Chinese marketplaces was 20,735 RMB/MT. Traders were more careful in purchasing goods and downstream industries purchased things on demand. As a result, the overall market demand for titanium dioxide was general.

    Barium sulfate, on the other hand, is usually mined from natural sources like barite or synthesized by reacting barium oxide (BaO) with sulfuric acid (H2SO4). Once both components are prepared, they are mixed in precise proportions to achieve the desired properties of lithopone.

    FAQ – EFSA 2021 safety assessment of titanium dioxide (E171)

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    1. Lithopone is used as an inert pigment in paints, inks and cosmetics.

    Lithopone, a zinc sulfide-based pigment, has been widely used in various industries due to its excellent whiteness, opacity, and chemical stability. Among the various grades of lithopone, 28B301 and 30B311 are particularly popular among manufacturers. In this article, we will provide a comprehensive guide on these two grades, including their properties, applications, and manufacturing processes.

    Figure 1: Process for the production of...
    Titanium Dioxide (TiO2) is an essential component in the coatings industry, playing a pivotal role in enhancing the performance and aesthetics of various coating products. In coatings factories worldwide, TiO2 is a critical raw material due to its unique properties that make it indispensable.

     

    Secondly, China's mature industrial infrastructure and advanced technology have enabled the country to achieve economies of scale in TiO2 production. The country's large-scale production facilities and efficient supply chain management systems have reduced production costs and increased output, further consolidating China's position in the global market.

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