(6) Polyvinyl chloride: As dispersant in the production of polyvinyl chloride, it is the main assistant in the preparation of PVC by suspension polymerization.
A study published in the Journal of Applied Toxicology evaluated the acute oral toxicity of HPMC in rats and found no side effects at doses up to 5000 mg/kg body weight (the highest dose tested). In addition, subchronic and chronic toxicity studies show no significant side effects in animals, even at high doses.
Key Players In the construction industry, HPMC thickens mortar, rendering it more workable and improving its cohesive properties. It also enhances the water retention capability, reducing the need for excessive water during application. This results in better durability and reduced cracking of the final product. As a leading MHEC manufacturer, we are committed to providing innovative solutions and exceptional customer service. Our team of experts has in-depth knowledge and experience in the development and production of cellulose ethers, ensuring the highest quality and performance of our products. We continuously invest in research and development to enhance our product offerings and meet the evolving needs of our customers.HPMC gels are commonly used in the pharmaceutical industry as matrices for controlled release drug delivery. Its ability to form a gel-like matrix helps sustain drug release over time, thereby prolonging therapeutic effects.
HPMC is used as a binder, water retention agent, and plasticizer in cement-based products, such as mortars, plasters, and grouts. It is also used as a water-soluble polymer in the production of gypsum board and as a rheology-modifying agent in paint and coatings.
In the absence of data, the FEEDAP Panel is not in the position to conclude on the safety of HPMC for the user.
Construction Industry On the other hand, HPMC, also a cellulose derivative, is synthesized by substituting hydroxyl groups with methyl and hydroxypropyl groups. This modification imparts it with unique properties, making it more resistant to degradation by enzymes and more soluble in cold water compared to HEC. HPMC is commonly employed in the food industry as a food additive, in the pharmaceutical industry as a film-forming agent for coatings, and as an emulsifier and stabilizer in cosmetics.Genotoxicity studies also indicate that HPMC is not mutagenic or genotoxic. Carcinogenicity studies have shown no evidence of potential carcinogenicity in animals treated with HPMC.
HPMC - High-Quality Solution for Sale Enhancing Performance in Various IndustriesThe etherification of cellulose disrupts the hydrogen bonding and the resulting compounds are not ionised and more water soluble. The EFSA ANS Panel (2018) concluded that modified celluloses including ethyl and methyl, hydroxypropyl celluloses, would not be absorbed intact and not fermented in the gastrointestinal tract of animals (rat) or humans; they are excreted essentially unchanged mainly via the faeces (more than 90% of the administrated doses), while only minor amounts of metabolites and derived-products are excreted via urine or expired air (as 14CO2) and there is no indication for accumulation in the body.
Hydroxyethyl cellulose (HEC) is a widely used polymer in various industries due to its exceptional thickening capabilities. It is a non-ionic, water-soluble derivative of cellulose, synthesized by the chemical modification of natural cellulose through the ethoxylation process. The thickening mechanism of HEC is a complex interplay of molecular interactions that result in the enhancement of the solution's viscosity. 4. Oral Care